AI Behind ChatGPT Could Help Spot Early Signs of Alzheimer's Disease. Research from Drexel University’s School of Biomedical Engineering, Science and Health Systems recently demonstrated that OpenAI’s GPT-3 program can identify clues from spontaneous speech that are 80% accurate in predicting the early stages of dementia.

Alzheimer’s disease is a currently incurable brain disorder. Speech, a quintessentially human ability, has emerged as an important biomarker of neurodegenerative disorders like AD. Can AI-driven speech analysis help identify AD? We show in this study that GPT-3, a specific language model produced by OpenAI, could be a step towards early prediction of AD through speech. Specifically, we demonstrate that text embedding, powered by GPT-3, can be reliably used to (1) distinguish individuals with AD from healthy controls, and (2) infer the subject’s cognitive testing score, both solely based on speech data. We further show that text embedding considerably outperforms the conventional feature-based approach and even performs competitively with the mainstream use of fine-tuned models. Our results suggest that there is a huge potential to develop and translate a fully deployable AI-driven tools for early diagnosis of dementia and direct tailored interventions to individual needs, thereby improving quality of life for individuals with dementia.

Source: https://journals.plos.org/digitalhealth/article?id=10.1371/journal.pdig.0000168